We live in an era of unprecedented technological, scientific and financial resources. I remain optimistic about the future, yet the risks to our world are increasing not reducing. They are systemic in nature and require a collective will to address them. Unfortunately, this is happening at exactly the time that nationalism, protectionism and populism are rising, and rules-based multilateralism is declining. I fear we may squander the opportunity to move towards a more sustainable, equitable and inclusive future. We must act together and we must act now.